"What can you do with nanosugar?"

Researchers' night 27.9.2019

Teaching nanochemistry 6.9.2019–29.11.2019

Fundamentals in Nanoscience NANS1001

Dr Helttunen

Dr Kaisa Helttunen

Academy Research Fellow at University of Jyväskylä 09/2017-

PhD in organic chemistry, University of Jyväskylä 2012

Research interests: supramolecular chemistry, anion binding, macrocyclic receptors (calix[4]pyrroles, resorcinarenes), and colloidal structures including micelles and solid lipid nanoparticles.

Research methods: synthesis, complexation studies (NMR, ITC, UV-vis, fluorescence), and crystallography.

Previous research includes cation complexation, Langmuir films and solid lipid nanoparticles of resorcinarene macrocycles, and anion complexes of aryl amide foldamers.


kaisa.j.helttunen (a) jyu.fi

Department of Chemistry
Nanoscience Center
P.O. Box 35
FI-40014 University of Jyväskylä



Picture of Lake Jyvaskyla

Macrocyclic Receptors for Selective Anion Extraction

May 2018 - April 2023

The project aims to offer pioneering solutions for the selective binding of biologically and technologically important anions. The target anions include anti-inflammatory drugs with carboxylate groups, and valuable resources, such as phosphate and precious metals (Au, Pt, Co). The project focuses on advanced synthesis of selective receptors, characterization of the anion complexes and development of extraction methods for target anions from water.

Go to project's page

University of Jyvaskyla

Recent Publications

  1. Kaisa Helttunen, Riia Annala, Aku Suhonen, Juho Iloniemi, Elina Kalenius, Gemma Aragay, Pablo Ballester, Heikki M. Tuononen, Maija Nissinen
    Oligoamide foldamers as helical chloride receptors – the influence of electron withdrawing substituents on anion binding interactions
    Chem. Asian J., 2019, 14, 647-654. doi:10.1002/asia.201801869 Graphical Abstract The incorporation of electron‐withdrawing substituents in aryl amide foldamers stabilizes the formation of 1:2 host–guest complexes with chloride anions.
  2. Kaisa Helttunen, Riia Annala, Aku Suhonen, Elisa Nauha, Juha Linnanto, Maija Nissinen
    Supramolecular chirality and symmetry breaking of fluoride complexes of achiral foldamers
    CrystEngComm, 2017, 19, 5184-5187. doi:10.1039/C7CE01109A Graphical Abstract Fluoride binding of achiral oligoamide foldamers produces polar and chiral crystal structures and induces exceptional symmetry breaking of the bulk sample.
  3. Kaisa Helttunen, Maija Nissinen
    Inverted molecular cups: 1-D and 2-D Ag(I) coordination polymers from resorcinarene bis-thiacrowns
    CrystEngComm, 2016, 18, 4944-4951. doi:10.1039/c6ce00243a Graphical Abstract Exo-cavity binding into resorcinarene based inverted molecular cups creates 1-D and 2-D silver coordination polymers with argentophilic interactions.
  4. Kaisa Helttunen, Albano Galán, Pablo Ballester, Johan Bergenholtz, Maija Nissinen
    Solid lipid nanoparticles from amphiphilic calixpyrroles
    J. Colloid Interface Sci., 2016, 464, 59-65. doi:10.1016/j.jcis.2015.11.012
  5. Aku Suhonen, Ian S. Morgan, Elisa Nauha, Kaisa Helttunen, Heikki M. Tuononen, Maija Nissinen
    The effect of a rigid sulfonamide bond on molecular folding: a case study
    Cryst. Growth Des., 2015, 15, 2602–2608. doi:10.1021/acs.cgd.5b00424

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